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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATP6V1H
All Species:
35.15
Human Site:
S345
Identified Species:
64.44
UniProt:
Q9UI12
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UI12
NP_057025.2
483
55883
S345
L
L
E
K
L
G
E
S
V
Q
D
L
S
S
F
Chimpanzee
Pan troglodytes
XP_001150191
483
55912
S345
L
L
E
K
L
G
E
S
V
Q
D
L
S
S
F
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_544082
483
55817
S345
L
L
E
K
L
G
E
S
V
Q
D
L
S
S
F
Cat
Felis silvestris
Mouse
Mus musculus
Q8BVE3
483
55836
S345
L
L
E
K
L
G
E
S
V
Q
D
L
S
S
F
Rat
Rattus norvegicus
NP_001013951
441
50841
L321
V
L
K
Q
L
E
N
L
E
Q
Q
K
Y
D
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515210
483
55883
S345
L
L
D
K
L
G
E
S
V
Q
D
L
S
S
F
Chicken
Gallus gallus
XP_423862
445
52062
D324
N
L
D
Q
Q
K
Y
D
D
E
D
I
S
E
D
Frog
Xenopus laevis
NP_001089309
479
55249
S341
L
L
E
K
L
G
E
S
V
Q
D
L
S
S
F
Zebra Danio
Brachydanio rerio
NP_775377
463
53422
S323
L
L
E
R
L
G
E
S
V
Q
D
L
S
S
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3J1
468
53715
S324
L
S
E
K
L
Q
N
S
V
Q
D
L
S
S
F
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q22494
470
54194
S332
L
T
E
E
L
T
L
S
V
H
D
L
S
S
Y
Sea Urchin
Strong. purpuratus
XP_783560
420
48731
T300
S
S
F
D
E
Y
S
T
E
V
K
S
G
R
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LX65
441
50266
S321
D
K
I
K
K
L
S
S
F
D
K
Y
K
Q
E
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.5
N.A.
98.5
N.A.
98.5
89
N.A.
96
78
91.5
85
N.A.
52.5
N.A.
50.9
54.6
Protein Similarity:
100
98.5
N.A.
98.7
N.A.
99.3
90.2
N.A.
98.1
84.2
94.1
90
N.A.
71.8
N.A.
66.4
68.5
P-Site Identity:
100
100
N.A.
100
N.A.
100
20
N.A.
93.3
20
100
93.3
N.A.
80
N.A.
60
0
P-Site Similarity:
100
100
N.A.
100
N.A.
100
40
N.A.
100
46.6
100
100
N.A.
80
N.A.
73.3
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
26.9
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
52.5
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
16
8
0
0
0
8
8
8
77
0
0
8
16
% D
% Glu:
0
0
62
8
8
8
54
0
16
8
0
0
0
8
8
% E
% Phe:
0
0
8
0
0
0
0
0
8
0
0
0
0
0
62
% F
% Gly:
0
0
0
0
0
54
0
0
0
0
0
0
8
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% H
% Ile:
0
0
8
0
0
0
0
0
0
0
0
8
0
0
0
% I
% Lys:
0
8
8
62
8
8
0
0
0
0
16
8
8
0
0
% K
% Leu:
70
70
0
0
77
8
8
8
0
0
0
70
0
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
0
0
0
16
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
16
8
8
0
0
0
70
8
0
0
8
0
% Q
% Arg:
0
0
0
8
0
0
0
0
0
0
0
0
0
8
0
% R
% Ser:
8
16
0
0
0
0
16
77
0
0
0
8
77
70
0
% S
% Thr:
0
8
0
0
0
8
0
8
0
0
0
0
0
0
0
% T
% Val:
8
0
0
0
0
0
0
0
70
8
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
8
0
0
0
0
8
8
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _